Solution:
It’s make a difference to. "the dampness began to affect my health" synonyms influence, exert influence on, have an effect on, act on, work on, condition, touch, have an impact on, impact on, take hold of, attack, infect, strike, strike at, hit; change, alter, modify, transform, form, shape, control, govern, determine, decide, guide, sway, bias"the climate was likely to be affected by greenhouse gas emissions"
Touch the feelings of move emotionally. "any one was visibly affected by the tragedy" upset, trouble, hit hard, overwhelm, devastate, damage, hurt, pain, grieve, sadden, distress, disturb, perturb, agitate, shake, shake up, stir; move, touch, tug at someone's heartstrings; make an impression on; informal knock back, bowl over, throw, faze, get to".
While,
Effect can be a noun or a verb whereas affect is a verb which explains ‘effect’.
This is the required solution.
