Proteins that interact with DNA often interact with the phosphates that are part of this molecule. Which of the following types of amino acids would you predict to be present in the DNA binding sites of these proteins?

a. acidic amino acids
b. nonpolar amino acids
c. uncharged polar amino acids
d. basic amino acids

Respuesta :

Answer: Option D) basic amino acids

Explanation:

Since the phosphates occupying the 5' end of DNA bear negative charge due to the previous dissociation of hydrogen atoms, ONLY portions of the interacting protein bearing positive charge serve as binding sites.

These portions of proteins with positive charge is made up of basic amino acids like lysine and arginine, as they have an extra amino acid in their side chain, and are attracted to phosphate molecules with negative charges.

Thus, basic amino acids will serve as binding sites

Answer: the correct option is D (basic amino acids).

Explanation: DNA binding site are part of DNA sequences where specific proteins ( DNA binding proteins) can bind. DNA binding proteins on the other hand are surrounded by domains which attracts single or double stranded DNA to its sites.

Some examples of DNA binding proteins includes:

- transcription factors

-polymerases

-nucleases and

- histones

Histonres are basic amino acids that binds to the acidic phosphate groups on DNA. I hope this helps. Thanks.