Respuesta :
Answer:
Synthesis is the phase of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase. Since accurate duplication of the genome is critical to successful cell division, the processes that occur during S-phase are tightly regulated and widely conserved.
Explanation:
If a cell has not properly copied its chromosomes or there is damage to the DNA, the CDK will not activate the S phase cyclin and the cell will not progress to the G2 phase. The cell will remain in S phase until the chromosomes are properly copied, or the cell will undergo programmed cell death.
Each step in the cell division is controlled and regulated by proteins like Cyclins. If a cell does not go through the S phase, it can not go to the G2 phase until the replication process is completed, or until it's programmed cell death.
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As the cell passes through different steps of cell division, there are auto control mechanisms to ensure that the step was correctly performed and the cell is ready to go to the next step.
Many regulator molecules act during the different stages of the mitosis process to make it possible.
There are too many factors interacting, activating, and deactivating to pass from one stage to another.
Cyclins are proteins that regulate the whole cell cycle. There are different types of cycling, each of them acting on a different stage.
When the cell is going through one of the stages, the only cyclin in high levels is the one that is regulating that cycle.
Once that stage is over, that cyclin concentration decreases, and the following one increases.
But if any step was not correctly performed, the cell can not pass to the following one.
During the S stage of the interphase occurs the DNI replication process.
At this point, also occurs the synthesis of histones and other associated proteins.
This is the only stage where the DNI molecule is replicated.
S phase cyclins are in charge of regulating the stage of DNA replication.
If the cell does not go through the S phase, the cyclins of this stage are not activated. And if S phase cyclins are not active, the cell can not go to the G2 phase.
The cell remains in the S phase until the DNA replication process is correctly done. And if it does not occur, the cell suffer programmed cell death.
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