contestada

HELP ME
Case Female pt, 35y • Complains: Discomfort in epigastria, periodic dull epigastric pain of low intensity after the meal, loss of appetite, belching with gas, food regurgitation, bad taste, excessive salivation, fatigue, unstable stool. Past medical history: Symptoms have started at the age of 23 with slow progression Has autoimmune thyroiditis Life history: Non smoker Mother has thyroiditis • Physical examination: Stable, satisfactory BMI 16,8 kg/m2 Skin Skin pale, dry BR 18/min Vesicular breathing, wheezing abs BP 125/85 mm Hg, HR 96/min Heart borders normal Heart sounds clear, murmurs abs Tongue thickened, with smoothed lingual papillae and teeth indentations, angular stomatitis. Abdomen distended, tympanites On superficial palpation soft, tender in epigastria Lower liver border under the right costal arch, soft, smooth, painless. Liver size 10x9x8sm Spleen is not enlarged Lab tests: CBC: HB 100 g/1, WBC 5,8x10%/1, differential (bands 4%, neutrophil 55%, cosinophils 1%, basophils 0%, monocytes 7%, lymphocytes 33%), ESR 23 mm/h. Gastric analysis: stomach in the fasting state is empty. Basal secretion: 18ml of the gastric juice, free acid 0%. Stimulated secretion after histamine: 15ml of the gastric juice, free acid 0%, pepsin 0,8g%. Esophagogastroduodenoscopy: gastric mucosa thin, pale, with smoothened folds and visible vascular network. Gastric biopsy: in tissue from antral, fundal parts glandular atrophy, intestinal metaplasia, HP is not detected Questions
1. List the syndromes
2. What is the preliminary diagnosis?
3. Choose additional diagnostic tests?
4. Prescribe treatment

Respuesta :

Answer:

Patients often complain of indigestion, but what do they mean? Indigestion is an old English word that means lack of adequate digestion, but patients and doctors interpret this in different ways. Many patients mean heartburn or acid regurgitation, the classic symptoms of gastro-oesophageal reflux disease. Some describe belching, abdominal rumblings, or even bad breath as indigestion. Others mean pain localised to the epigastrium or a non-painful discomfort in the upper abdomen which may be described as fullness, bloating, or an inability to finish a normal meal (early satiety). Dyspepsia is best restricted to mean pain or discomfort centred in the upper abdomen.

Major structural causes of dyspepsia

Chronic peptic ulcer (duodenal or gastric)

Gastro-oesophageal reflux disease (>50% have no oesophagitis)

Gastric or oesophageal adenocarcinoma (rare but of concern for patient and doctor)

There are many causes of dyspepsia, but at least two thirds of patients have no structural or biochemical explanation for their symptoms. It has been suggested that dyspepsia can be subdivided based on groups (or clusters) of symptoms. However, subgroups have not proved to be of value in identifying the underlying cause of dyspepsia and overlap considerably. Some patients report having troublesome burping associated with abdominal bloating or discomfort that is transiently relieved by bringing up the wind. These patients have aerophagy, and repeated swallowing of air may be obvious during the consultation.

Go to:

Causes of dyspepsia

History taking is key to identifying the likely cause of dyspepsia.

Gastro-oesophageal reflux disease

It is important and practical to distinguish gastro-oesophageal reflux disease (GORD) from dyspepsia. Frequent heartburn is a cardinal symptom of GORD; acid reflux causes a retrosternal or epigastric burning feeling that characteristically radiates up towards the throat, is relieved transiently by antacids, and is precipitated by a meal or by lying down.

Explanation: