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Which pre-B cell marker is used exclusively in the work-up of acute leukemia in studying B lineage ALL (acute lymphoblastic Leukemia)

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Answer:

To study leukemias that affect cells of the adaptive immune system, cells of the lymphoid lineage such as B cells and T cells are labeled. The expression of CD19 (Figure 3) is specific to the B cell lineage, and is maintained throughout differentiation and even neoplastic transformation, making it useful in the diagnosis of leukaemia 2.

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