In the outbreak of malaria, the frequency of the recessive allele for the HbS gene will increase. The correct option is A.
What is the HbS gene?
HbS is a beta-globin gene known as sickle hemoglobin.
It causes sickle cell disease in humans.
The disease is expressed by two HbS variants or one HbS variant or one another beta-globin gene.
Malaria is caused by the plasmodium parasite, which is present in the saliva of the mosquito.
Thus, the correct option is A, the frequency will increase.
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