A newly synthesized protein destined for secretion from a eukaryotic cell will generally follow which of the pathways listed below, starting with where it was synthesized?
There is only one correct answer for this question.
A) ribosome â†’rough ER â†’ smooth ER â†’Golgi â†’ transport vesicle â†’ nucleus
B) Golgi â†’ rough ER â†’ lysosome â†’ transport vesicle â†’ plasma membrane
C) ribosome â†’rough ER â†’ transport vesicle â†’ Golgi â†’ transport vesicle â†’ plasma membrane
D) rough ER â†’ lysosome â†’ribosomeâ†’ transport vesicle â†’ plasma membrane

C. Is the correct answer.

The protein is synthesized by the ribosome directly into rough ER (guided by signal sequence) the signal sequence is cleaved off and the protein is transported to golgi apparatus in vesicle. Golgi processes and packages protein into another vesicle which is transported to the cell membrane.

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