In human and many other eukaryotic species' cells, the nuclear membrane has to disappear to permit the attachment of microtubules to kinetochores.
Eukaryotic cells' cytoskeleton is made up of tubulin polymers called microtubules, which give eukaryotic cells their shape and structure. Microtubules can measure up to 50 micrometers in length, 23 to 27 nm in width, and 11 to 15 nm in inner diameter. They are created when the two globular proteins alpha and beta tubulin polymerize into protofilaments, which can later interact to form a hollow tube called a microtubule. 13 protofilaments are arranged in a tubular configuration to make up the most prevalent type of microtubule. One of the cytoskeletal filament systems in eukaryotic cells is the microtubule network.
Thus from above conclusion we can say that in human and many other eukaryotic species' cells, the nuclear membrane has to disappear to permit the attachment of microtubules to kinetochores.
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