Hypocalcemia stimulates secretion of pth
What is hypocalcemia?
Hypocalcemia is a medical condition characterized by low calcium levels in the blood serum. The normal range of blood calcium is 2.1-2.6 mmol/L (8.8-10.7 mg/dL, 4.3-5.2 mEq/L), while levels less than 2.1 mmol/L are considered hypocalcemic. Mildly low levels that develop slowly frequently have no symptoms. Other symptoms may include numbness, muscle spasms, seizures, confusion, or cardiac arrest.
Idiopathic hypoparathyroidism is the most common cause of hypocalcemia. Other causes include hypoparathyroidism, vitamin D deficiency, kidney failure, pancreatitis, calcium channel blocker overdose, rhabdomyolysis, tumor lysis syndrome, and medications such as bisphosphonates or denosumab. In most cases, a corrected calcium or ionized calcium level should be used to confirm the diagnosis. An electrocardiogram can reveal specific changes (ECG).
Hence, hypocalcemia stimulates secretion of pth.
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