IgA are the antibodies that are found in mucosal secretions and help to protect the respiratory system from infection.
Large populations of commensal bacteria are present on mucosal surfaces, which serve as the main point of entry for pathogenic organisms. Mucosal B cells release a significant number of immunoglobulin (Ig) molecules via various mechanisms to thwart microbial entry. The mucosal membranes of the intestines are home to the bulk of plasma cells that produce IgA.
Secretory IgA, the main kind of antibody found on mucous membranes, works primarily by binding germs and preventing them from coming into touch with host tissues. Uncertainty exists over the best method of immunization to induce a secretory IgA response.
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