Respuesta :
It is correct that the Genome browser information on the TP53 gene is track A provides genetic evidence of functionality.
A tumour suppressor protein with transcriptional activation, DNA binding, and oligomerization domains is encoded by this gene. The encoded protein reacts to various cellular stressors by controlling target gene expression, which causes cell cycle arrest, apoptosis, senescence, DNA repair, or adjustments in metabolism. A number of human cancers, including hereditary tumours like Li-Fraumeni syndrome, are linked to mutations in this gene. Multiple transcript variants and isoforms are produced by alternative splicing of this gene and the utilisation of alternative promoters. It has also been demonstrated that different translation beginning codons from identical transcript variants produce multiple isoforms.
Hence, TP53 is involved in basic cell functioning.
To know more about Apoptosis.
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