A single point mutation in the gene encoding ras protein allows this protein to stay in an active form for longer periods, even in the absence of a signal. Therefore, this gene is an oncogene.
A cancer metastatic pathway can be defined as the uncontrolled cell division process that suffers a given cell type, which is often associated with the activation of genes that lead to cancer called oncogenes.
Oncogenes can be activated by the emergence of mutations such as point mutations, which are genetic alterations that may modify the resulting protein such as here the ras protein.
Therefore, with this data, we can see that a cancer metastatic pathway can be activated as a response to a mutation in an oncogene, which is uncontrolled in cancer and may lead to successive cycles of cell division.
Learn more about cancer metastatic pathways and oncogenes here:
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