Answer:
3 and 4
Explanation:
Skin rash: This is a possible side effect of locally administered antibiotics. Some individuals may experience an allergic reaction or irritation at the site of application, resulting in a skin rash.
Allergic reactions: Allergic reactions can occur with locally administered antibiotics, just as they can with systemic administration. These reactions can range from mild itching and redness to more severe symptoms such as swelling and difficulty breathing.
